Monroe County was created by the Mississippi Territorial Governor David Holmes on 1815 June 29. It comprised all the Creek Indian lands ceded by the Treaty of Fort Jackson. It was reduced in size by the creation of the Alabama counties of Montgomery, Conecuh and Wilcox. It was named for U.S. President James Monroe. Monroe County is located in the southwestern area of the state, in the Piney Woods region. It encompasses 1,019 square miles.